EUTrigTreat Publications

15 May 2015, Borile G. et. al: Multispot multiphoton Ca2+ imaging in acute myocardial slices. PMID 25517401, OPEN ACCESS

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16 December 2014, Walker MA. et. al: Superresolution Modeling of Calcium Release in the Heart. PMID 25517166 OPEN ACCESS

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15 December 2014, AzimiHashemi N. et. al: Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optigenetic tools. PMID: 25503804

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18 November 2014,Gillet L. et. al: Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current. PMID: 25447080 OPEN ACCESS

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7 November 2014, Shy D et al.: Targeting the sodium channel NaV1.5 to specific membrane compartments of cardiac cells: Not a simple task!. PMID: 25378529

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21 October 2014, Crocini C et al.: Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure. PMID: 25288764 OPEN ACCESS

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20 October 2014, Greiser M et al.: Tachycardia-induced silencing of subcellular Ca2+ signaling in atrial myocytes. PMID: 25329692

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15 October 2014, Wagner E et al.: Analysis of tubular membrane networks in cardiac myocytes from atria and ventricles. doi:10.3791/51823 OPEN ACCESS

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8 September 2014, Dura M et al.: Toward panoramic in situ mapping of action potential propagation in transgenic hearts to investigate initiation and therapeutic control of arrhythmias. PMID: 25249982  OPEN ACCESS

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23 June 2014, Parlitz U et al.: Local observability of state variables and parameters in nonlinear modeling quantified by delay reconstruction. PMID: 24985465 OPEN ACCESS

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3 June 2014, Shy D et al.: PDZ domain binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function. PMID: 24895455

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27 May 2014, Vafiadaki E et al.: Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differntiation. PMID: 24860983

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14 May 2014, Parlitz U et al: Quantifying uncertainty in state and parameter estimation. DOI: 10.1103/PhysRevE.89.050902 OPEN ACCESS

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1 May 2014, Zaglia T et al.: Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy. PMID: 24789905

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26 February 2014, Arakel EC et al.: Tuning the electrical properties of the heart by differential trafficking of KATP ion channel compleses. PMID: 24569881 OPEN ACCESS

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3 January 2014, Ward CW et al.: Mechanical stretch-induced activation of ROS/RNS signaling in striated muscle. PMID: 23971496 OPEN ACCESS

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15 November 2013, Varkevisser R et al.: Vernakalant is devoid of proarrhythmic effects in the complete AV block dog model. PMID: 24211677

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14 November 2013, Vafiadaki E et al.: Identification of a Protein Phosphatase-1/Phospholamban Complex That Is Regulated by cAMP-Dependent Phosphorylation. PMID: 24244723 OPEN ACCESS

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6 November 2013, Marynissen T et al.: Heart rate turbulence predicts ICD-resistant mortality in ischaemic heart disease. PMID: 24196450

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30 September 2013, Dries E et al.: Selective Modulation of Coupled Ryanodine Receptors During Microdomain Activation of CaMKII in the Dyadic Cleft. PMID: 24081880

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25 August 2013, Ward CW et al.: Mechanical stretch induced activation of ROS/RNS signaling in striated muscle. PMID: 23971496

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24 August 2013, Floré V et al.: Can body surface microvolt T-wave alternans distinguish concordant and discordant intracardiac alternans? PMID: 23614703

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16 August 2013, Hohendanner F et al.: Intracellular dyssynchrony of diastolic cytosolic [Ca 2+] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure. PMID: 23825358

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12 July 2013, Ferrantini C et al.: The transverse-axial tubular system of cardiomyocytes. PMID: 23846763 OPEN ACCESS

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1 July 2013, Varkevisser R et al.: Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue. PMID: 23586323 OPEN ACCESS

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25 June 2013, Parlitz U et al.: Identification of equivalent dynamics using ordinal pattern distributions. PMID: OPEN ACCESS

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25 June 2013, Williams GS et al.: Mitochondrial calcium uptake. PMID: 23759742

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3 June 2013, Kelly A et al.: Sub-Epicardial Action Potential Characteristics Are a Function of Depth and Activation Sequence in Isolated Rabbit Hearts. PMID: 23733913

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2 June 2013, Akerboom J et al.: Genetically encoded caldium indicators for multi-color neural activity imaging and combination with optogenetics. PMID: 23459413 OPEN ACCESS

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1 June 2013, Boyman L et al.: NCLX: the mitochondrial sodium calcium exchanger. PMID: 23538132 OPEN ACCESS

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12 May 2013, Manella CA et al.: The connection between inner membrane topology and mitochondrial function. PMID: 23672826 OPEN ACCESS

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1 May 2013, Sipido KR, Cheng H: T-tubules and ryanodine receptor microdomains: on the road to translation. PMID:23554456

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1 May 2013, Kohl T et al.: Imaging T-tubules: dynamic membrane structures for deep fuctions. PMID: 23504549 OPEN ACCESS

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1 May 2013, Prosser BL et al.: X-ROS signalling is enhanced and graded by cyclic cardiomyocyte stretch. PMID: 23524301

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19 April 2013, Gizzi A et al.: Effects of pacing site and stimulation history on alternans dynamics and the development of complex spatiotemporal patterns in cardiac tissue. PMID: 23637684 OPEN ACCESS

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10 April 2013, Wijers SC et al.: Implementation of guidelines for implantable cardioverter-defibrillator therapy in clinical practice: Which patients do benefit? PMID: 23572330 OPEN ACCESS

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1 April 2013, Bourgonje VJ et al.: Combined Na+/Ca 2+ exchanger and L-type calcium channel block as a potential strategy to suppress arrhythmias and maintain ventricular function. PMID: 23515266

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15 March 2013, Schumann-Bischoff J et al.: Nonlinear system identification employing automatic differentiation. http://ds.doi.org/10.1016/j.cnsns.2013.02.017

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1 January 2013, Sipido KR et al.: T-tubules remodelling and ryanodine receptor organization modulate sodium-calcium exchange. PMID: 23224896

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6 December 2012, Prosser BL et al.: X-ROS signaling in the heart and skeletal muscle: stretch-dependent local ROS regulates [Ca2+]i. PMID: 23220288

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3 December 2012, Kohl T et al.: Superresolution microscopy in heart - cardiac nanoscopy. PMID: 23219451

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29 November 2012, Varkevisser R et al.: Inhibiting the clathrin-mediated endocytosis pathway rescues K(IR)2.1 downregulation by pentamidine. PMID: 23192368

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31 October 2012, Shy D et al.: Cardiac sodium channel NaV1.5 distribution in myocytes via interacting proteins: the multiple pool model. PMID: 23123192 OPEN ACCESS

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12 October 2012, Lehnart SE: Understanding the physiology of heart failure through cellular and in vivo models towards targeting of complex mechanisms. PMID: 23064508


17 September 2012, Suetani H et al.: Manifold Learning Approach for Reconstructing Internal States and Data Assimilation from Observations of Chaotic Dynamical Systems. PMID: 23030999 OPEN ACCESS

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14 September 2012, Lam CK et al.: Novel Role of HAX-1 in Ischemic Injury Protection: Involvement of Hsp90. PMID: 22982986

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14 September 2012, Bittihn P et al.: Negative curvature boundaries as wave emitting sites for the control of biological excitable media. PMID: 23005683


28 August 2012; Lehnart: Destroying and restoring cardiomyocyte architecture. Session number: 964

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19 July 2012, Hagen BM et al.: A comparative assessment of fluo Ca2+ indicators in rat ventricular myocytes. PMID: 22721780


16 July 2012, Husson SJ et al.: Microbial Light-Activatable Proton Pumps as Neuronal Inhibitors to Functionally Dissect Neuronal Networks in C. elegans. PMID: 22815873 OPEN ACCESS


10 July 2012, Laurent G et al.: Multifocal Ectopic Purkinje-Related Premature Contractions: A New SCN5A-Related Cardiac Channelopathy. PMID: 22766342

22 June 2012, Derangeon M et al.: Mouse Models of SCN5A-Related Cardiac Arrhythmias. PMID: 22737129 OPEN ACCESS


21 June 2012, Wagner E et al.: STED Live Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction. PMID: 22723297

8 June 2012, Elliott EB et al.: Isolated Rabbit Working Heart Function During Progressive Inhibition of Myocardial SERCA Activity. PMID: 22556337

15 May 2012, Varkevisser R et al.: Beat-to-beat variability of repolarization as a new biomarker for pro-arrhythmia in vivo. PMID: 22609158

4 May 2012, Lederer WJ et al.: Cell biology. Superresolution subspace signaling. PMID: 22556238

14 April 2012, Wijers SC et al.: Microvolt T-wave alternans in an unselected heart failure population: pros and cons. PMID: 22431405

12 March 2012, Sacconi L et al.: Action potential propagation in transverse-axial tubular system is impaired in heart failure. PMID: 22451916 OPEN ACCESS

12 March 2012, Cai WF et al.: Ablation of Junctin or Triadin is Associated with Increased Cardiac Injury Following Ischemia-Reperfusion. PMID: 22411973 OPEN ACCESS

14 February 2012, Brochet at al.: Elementary calcium release events from the sarcoplasmic reticulum in the heart. PMID: 22453956 OPEN ACCESS
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20 December 2011, Stams TR et al.: Verapamil as an antiarrhythmic in congestive heart failure: hopping from rabbit to human? PMID: 22188337

13 December 2011, Martewicz S et al.: Reversible alteration of calcium dynamics in cardiomyocytes during acute hypoxia transient in a microfluidic platform. PMID: 22158991

 2 December 2011, Plazzo AP et al.: Bioinformatic and mutational analysis of channelrhodopsin-2 cation conducting pathway. PMID: 22139833 OPEN ACCESS


23 November 2011, Schumann-Bischoff J and Parlitz U: State and parameter estimation using unconstrained optimization. PMID: 22181491

23 November 2011, Seegers J et al.: Rationale, objectives, and design of the EUTrigTreat clinical study: a prospective observational study for arrhythmia risk stratification and assessment of interrelationships among repolarization markers and genotype. PMID: 22117037 OPEN ACCESS
 

13 October 2011, Biesmans L et al.: Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density. PMID: 22022376 OPEN ACCESS

12 October 2011, Lehnart SE: Combined neuro-cardiogenic epilepsy syndromes and novel mechanistic insights. Novel Aspects on Epilepsy, ISBN 978-953-307-678-2

6 October 2011, Stams TR et al.: Effects of K201 on repolarization and arrhythmogenesis in anesthetized chronic atrioventricular block dogs susceptible to dofetilide-induced torsade de pointes. PMID: 22001562

21 September 2011, Berg S et al.: Synchronization based system identification of an extended excitable system. PMID: 21974639

20 September 2011, Williams GS et al.: Dynamics of calcium sparks and calcium leak in the heart. PMID: 21943409 OPEN ACCESS

9 September 2011, Prosser BL et al.: X-ROS signaling: rapid mechano-chemo transduction in heart. PMID: 21903813

16 August 2011, Chikando AC et al.: Ca2+ dynamics in the mitochondria - state of the art. PMID: 21864537

8 July 2011, Han P et al.: Catecholaminergic Induced Arrhythmias in Failing Cardiomyocytes Associated with Human HRCS96A Variant Overexpression. PMID: 21742996 OPEN ACCESS

30 June 2011, Nalos L et al.: Comparison of I(Kr) blocking drugs Moxifloxacin and Dofetilide/E-4031 in 5 screening models of pro-arrhythmia reveals insufficient specificity of isolated cardiomyocytes. PMID: 21718297 OPEN ACCESS

20 May 2011, Parlitz U et al.: Synchronization patterns in transient spiral wave dynamics. PMID: 21728699

19 April 2011, Parlitz U et al.: Classifying cardiac biosignals using ordinal pattern statistics and symbolic dynamics. PMID: 21511252

14 April 2011, Qian J et al., 2011:Small Heat Shock Protein 20 Interacts With Protein Phosphatase-1 and Enhances Sarcoplasmic Reticulum Calcium Cycling. PMID: 21493896 OPEN ACCESS

8 March 2011, Acsai K et al.: Microdomain [Ca2+] near ryanodine receptors as reported by L-type Ca2+ and Na/Ca exchange currents. PMID: 21486798 OPEN ACCESS

18 Feb. 2011, Floré V et al.: Microvolt t-wave alternans and beat-to-beat variability of repolarization during early post-ischemic remodeling in a pig heart. PMID: 21338712

25 Jan. 2011, Wang HS et al.: SERCA2a Superinhibition by Human Phospholamban Triggers Electrical and Structural Remodelling in Mouse Hearts. PMID: 21266500 OPEN ACCESS

16 Dec. 2010, Petitprez S et al.: SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes. PMID: 21164104 OPEN ACCESS

9 Dec. 2010, Myles RC et al.: Alternans of action potential duration and amplitude in rabbits with left ventricular dysfunction following myocardial infarction. PMID: 21145895

9 Dec. 2010, Brochet DX et al.: Quarky calcium release in the heart. PMID: 21148431 OPEN ACCESS

14 Oct. 2010, Albesa M et al.: Regulation of the cardiac sodium channel Nav1.5 by utrophin in dystrophin-deficient mice. PMID: 20952415 OPEN ACCESS

1 October 2010, Lehnart SE et al.: How can clacium leaks occur within heart cells?, Dialogues in Cardiovascular Medicine-Vol 15 No 4 2010

17 Sep. 2010, Santana LF et al.: How does the shape of the cardiac action potential control calcium signaling and contraction in the heart? PMID: 20850450

22 Aug. 2010, Arvanitis DA et al.: Histidine-rich calcium binding protein: the new regulator of sarcoplasmic reticulum calcium cycling. PMID: 20807542 OPEN ACCESS

10 Aug. 2010, Prosser BL et al.: Subcellular Ca2+ signaling in the heart: the role of ryanodine receptor sensitivity. PubMed, PMID: 20660656 OPEN ACCESS

 
 
14 July 2010, Hellenkamp K et al.: Ryanodine Receptor stabilisators as a new strategy for the treatment of arrhythmia and heart failure, Der Kardiologe 4-2010

20 May 2010, Vos MA: The quest for an anti-arrhythmic drug against atrial fibrillation that combines efficacy with safety. PMID: 20488855 OPEN ACCESS

2010, Vafiadaki E et al.: Pharmacogenetically tailored treatments for heart disease. PMID: 20459385

26 Nov. 2009, Lehnart SE and Lederer WJ: An antidote for calcium leak: targeting molecular arrhythmia mechanisms. PMID: 19931542 OPEN ACCESS